Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome

Authors

  • Yu.M. Stepanov State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”, Dnipro, Ukraine
  • I.Ya. Budzak State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine
  • I.A. Klenina State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”, Dnipro, Ukraine

DOI:

https://doi.org/10.22141/2308-2097.53.3.2019.181470

Keywords:

irritable bowel syndrome, gut microbiota, dysbiosis, short-chain fatty acids

Abstract

The article presents the issues related to gut microbiota and short-chain fatty acids in patients with irritable bowel syndrome. It was found that the faecal concentration of acetic, propionic, butyric acids is higher in patients with irritable bowel syndrome with diarrhea, compared with the patients without diarrhea syndrome. 83.3–88.9% of patients with various forms of irritable bowel syndrome presented with dysbiotic changes. The reduced concentration of Bifidobacterium species, mainly lactic acid bacteria, is more often registered in patients with diarrheal form. There is a certain correlation between the concentration of short-chain fatty acids and the content of Bifidobacterium, Lactobacillus, Candida and opportunistic bacteria.

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References

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Published

2021-09-06

How to Cite

Stepanov, Y., Budzak, I., & Klenina, I. (2021). Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome. GASTROENTEROLOGY, 53(3), 178–181. https://doi.org/10.22141/2308-2097.53.3.2019.181470

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Original Researches

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