Short-chain fatty acids: the role in the development of irritable bowel syndrome

Authors

  • Yu.M. Stepanov State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”, Dnipro, Ukraine
  • I.Ya. Budzak State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine
  • I.A. Klenina State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”, Dnipro, Ukraine

DOI:

https://doi.org/10.22141/2308-2097.53.1.2019.163458

Keywords:

irritable bowel syndrome, pathogenesis, intestinal microflora, short-chain fatty acids

Abstract

The article deals with the concepts of irritable bowel syndrome. A brief analysis of probable factors of irritable bowel syndrome development was performed. The role of intestinal microflora and the contribution of short-chain fatty acids to the processes occurring in the irritable bowel syndrosme are considered in detail. There were analyzed the studies of different authors concerning short-chain fatty acids. The results of own studies evaluating fecal content of short-chain fatty acids in patients with irritable bowel syndrome are shown. There was revealed a significant increase in the level of short-chain fatty acids, especially in diarrheal form of irritable bowel syndrome.

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Published

2021-09-07

How to Cite

Stepanov, Y., Budzak, I., & Klenina, I. (2021). Short-chain fatty acids: the role in the development of irritable bowel syndrome. GASTROENTEROLOGY, 53(1), 49–53. https://doi.org/10.22141/2308-2097.53.1.2019.163458

Issue

Vol. 53 No. 1 (2019)

Section

Original Researches

License

Copyright (c) 2019 Yu.M. Stepanov, I.Ya. Budzak, I.A. Klenina

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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