Clinical and Endoscopic Aspects of Mucousal Candidosis of the Upper Gastrointestinal Tract in Patients with Gastroenterological Diseases

I.V Kushnirenko, L.M. Mosiychuk, O.O. Krylova, L.I. Belova, L.V. Demeshkina

Abstract


The article resolves of actual problem of interrelation of clinical and endoscopic aspects of mucosal candidosis in upper part of digestive tract. The results of investigation performed in 122 patients led to reveal the prevalence of dyspeptic syndrome in patients with this pathology, in patients with esophageal disorder the intensity of abdominal pain syndrome was 1.5 times higher than in group with only oropharyngeal candidosis (p < 0.001). The deeper mucosal disorder by Candida was associated with increase of frequency of revealing macroscopic signs of esophageal inflammation (р < 0.05), fur (r = 0.220; р = 0.02), difficulty of food pass through the esophagus (r = 0.235; р = 0.02), retrosternal pain (r = 0.249; р = 0.01) with absence of influence of such inflammatory factors as gastroesophageal and duodenogastral refluxes. There was revealed the direct relation of macroscopic signs of inflammation and postulcerative deformation in duodenal bulb with mucosal candidosis degree (r = 0.250; р = 0.01). On the whole the analysis of received data showed the necessity of further study of the role of opportunistic infection in formation pathological process and development of diseases.


Keywords


Candida spp.; mucosa; esophagus; oropharyngeal candidosis; inflammation

References


Arіkan S. Correlation of In Vitro Fluconazole Susceptibility with Clinical Outcome for Severely іll Patients with Oropharyngeal Candidiasis / Arіkan S., Akova M., Hayran M. // Clinical Infectious Diseases. — 1998. — № 26. — P. 903-908.

Kwok M.H. The use of topical nonabsorbable gastrointestinal antifungal prophylaxis to prevent fungal infections in critically ill immunocompetent patients: A meta-analysis / M.H. Kwok,

S.A. Rochford, G. John // Critical care medicine. — 2005. — Vol. 33, № 10. — P. 2383-2392.

Risk factors for albicans and non-albicans candidemia in the intensive care unit / Chow J.K., Golan Y., Ruthazer R. [et al.] // Crit. Care Med. — 2008. — № 36(7). — P. 1993-1998.

Левончук Е.А. Кандидозы слизистых оболочек полости рта / Е.А. Левончук // Современная стоматология. — 2006. — № 3. — С. 27-32.

Микробиология и иммунология для стоматологов: [пер. с англ.] / Под ред. Р.Дж. Ламонта, М.С. Лантц, Р.А. Берне, Д.Дж. Лебланка; пер. с англ. под ред. В.К. Леонтьева. — М.: Практическая медицина, 2010. — 504 с.

Abraham C.M. Advances and Emerging Techniques in the Identification, Diagnosis and Treatment of Oral Candidiasis / C.M. Abraham // Pathology Journal. — 2011. — № 5. — С. 8-12.

Liu X.-H. Intestinal colonization with Candida albicans and mucosal Immunity / X.-D. Bai, X.-H. Liu, Q.-Y. Tong // World J. Gastroenterol. — 2004. — № 10(14). —

P. 2124-2126.

Calderone R.A. Virulence factors of Candida albicans / R.A. Calderone, W.A. Fonzi // Trends Microbiol. — 2001. — № 9. — Р. 327-335.

Zunt S.L. Oral Candidiasis: Diagnosis and Treatment /

S.L. Zunt // The Journal of Practical Hygiene. — 2000. — № 9(5). — Р. 31-36.

Kliemann D.A. Candida esophagitis: species distribution and risk factors for infection / D.A. Kliemann, A.C. Pasqualotto, M. Falavigna [et al.] // Rev. Inst. Med. Trop. S. Paulo. — 2008. — № 50(5). — Р. 261-263.

Oropharyngeal Candidiasis as a Marker for Esophageal Candidiasis in Patients with Cancer /

G. Samonis, P. Skordilis, S. Maraki [et al.] // Clin. Inf. Dis. — 1998. — № 27. — Р. 283-286.

Минимальная стандартная терминология в эндоскопии пищеварительной системы: пособие для врачей /

Е.Д. Федоров, С.Ю.Орлов, П.Л. Чернякевич [и др.]. — М.: ЗАО «Бизнес-школа «Интел-Синтез», 2001. — 80 с.

Эндоскопические классификации и комментарии к ним / В.И. Никишаев, Е.О. Врублевская, И.И. Лемко. — К.: Гама-колір, 2004. — 32 с.

Кудряшова И.В. Ранняя диагностика хронического панкреатита с позиции использования ультразвуковой томографии и индекса качества жизни: методические рекомендации / Кудряшова И.В. — Смоленск,

— 20 с.




DOI: https://doi.org/10.22141/2308-2097.3.49.2013.86270

Refbacks

  • There are currently no refbacks.


Copyright (c) 2016 GASTROENTEROLOGY

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru