Liver Stiffness According to Data of Shear Wave Elastography in Patients with Diabetes Mellitus Type 2 and Nonalcoholic Fatty Liver Disease Depending on Activity of NAFLD

O.B. Dynnyk, G.P. Mykhalchishin, N.M. Kobyliak, P.M. Bodnar

Abstract


Shear wave elastography is one of the most promising non-invasive methods for diagnosis of fibrosis and steatosis in chronic diffuse liver diseases, which can be used as an alternative to biopsy. Given its widespread introduction into clinical practice, the groups of scientists from around the world pay more attention to the study of factors that can affect the measurement and its diagnostic efficacy. Our research devoted to the study of liver parenchyma stiffness changes measured by shear wave elastography/elastometry in patients with nonalcoholic fatty liver disease, according to univariate correlation and multiple linear regression analysis data, showed that independent determinants associated with increasing of liver parenchyma stiffness were degree of insulin resistance, obesity and transaminase activity.


Keywords


shear wave elastography; stiffness of liver parenchyma; nonalcoholic fatty liver disease; transaminase activity; necroinflammatory syndrome

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DOI: https://doi.org/10.22141/2308-2097.3.53.2014.82104

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