Intravenous form of omeprazole will be replaced by oral form in patients with ulcer bleeding

A.V. Savustyanenko

Abstract


The results of the research suggest the same therapeutic efficacy of oral and intravenous forms of omeprazole in patients with peptic ulcer bleeding. This formulation should be administered at a high dose (orally first dose of 80 mg and then 40 mg every 12 hours). Use of oral omeprazole is more cost-effective due to the cheaper cost of pills and the ability to discharge patients from a hospital in the earlier terms Proton pump inhibitors are more effective and more cost-effective compared to H2-blokers in patients with ulcer blee-ding. Most researchers believe that in the nearest future will be need to revise existing guidelines for the management of patients with ulcer bleeding in favor of replacing the recommendations on the use of intravenous forms of proton pump inhibitors on oral.


Keywords


omeprazole; proton pump inhibitors; oral form; intravenous form; ulcer bleeding

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DOI: https://doi.org/10.22141/2308-2097.4.54.2014.82087

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