Investigation of the Quality of Life Indicators According to SF-8 in Patients with Functional Gastrointestinal Disorders

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A.E. Dorofeiev
T.Ye. Kuhler
A.Yu. Butova


Quality of life (QOL) — a very important method which can improve the communication between a doctor and a patient, identifying the impact of the disease on the physical, mental and social well-being of a patient, the effectiveness of the therapy and the development of rehabilitation programs. The objective of the study was to investigate the psychosomatic characteristics and QOL of patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). This study was cross-sectional. It included 80 patients with FD and 93 patients with IBS according to the Rome criteria III, as well as a control group of 30 healthy volunteers. We assessed health-related QOL by the standard 4-week form of SF-8 questionnaire. When comparing the level of QOL in patients with FD and IBS, we revealed significant deterioration compared with the control group, but there were no statistically significant differences between them (p < 0.05).

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How to Cite
Dorofeiev, A., Kuhler, T., & Butova, A. (2015). Investigation of the Quality of Life Indicators According to SF-8 in Patients with Functional Gastrointestinal Disorders. GASTROENTEROLOGY, (2.56), 53–58.
Original Researches


Дорофеев А.Э. Функциональная диспепсия: современные представления, механизмы и тактика ведения пациентов / А.Э. Дорофеев, О.В. Томаш, Н.Н. Руденко // Новости медицины и фармации (Гастроэнтерология). — 2012. — С. 407.

Vanheel H. Changes in gastrointestinal tract function and structure in functional dyspepsia / H. Vanheel, R. Farré // Nat. Rev. Gastroenterol. Hepatol. — 2013. — Vol. 10. — P. 142-149. — Doi:10.1038/nrgastro.2012.255

An evidence-based systematic review on the management of irritable bowel syndrome / L.J. Brandt, W.D. Chey, A.E. Foxx-Orenstein [et al.] // Am. J. Gastroenterol. — 2009. — Vol. 104(Suppl. 1). — P. S1-S35.

Concomitant functional dyspepsia and irritable bowel syndrome decrease health-related quality of life in gastroesophageal reflux di-sease / De Vries D.R., M.A. van Herwaarden, A. Baron [et al.] // Scand. J. Gastroenterol. — 2007 Aug. — Vol. 42(8). — Р. 951-6.

World Gastroenterology Organisation Global Guideline / Quigley E., Fried M., Gwee K.A. [et al.] // Irritable bowel syndrome: a global perspective. — 2009. 6. Ohman L. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions / L. Ohman, M. Simrén // Nat. Rev. Gastroenterol. Hepatol. — 2010. — V. 7. — P. 163-173.

Jae Myung Park Functional Gastrointestinal Disorders Diagnosed by Rome III Questionnaire in Korea / Jae Myung Park, Myung-Gyu Choi // Journal of Neurogastroenterology and Moti-lity. — 2011. — № 17(3). — P. 279-286. 8. Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators / T. Piche, G. Barbara, P. Aubert [et al.] // Gut. — 2009. — V. 58. — P. 196-201.

Дорофеев А.Э. Синдром раздраженного кишечника — современный взгляд на проблему / А.Э. Дорофеев, О.А. Рассохина // Новости медицины и фармации (Гастроэнтерология). — 2011. — С. 358.

Tack J. Functional dyspepsia — symptoms, definitions and validity of the Rome III criteria / J. Tack, N.J. Talley // Nat. Rev. Gastroenterol. Hepatol. — 2013. — Vol. 10. — P. 134-14. — Doi: 10.103 8/nrgastro.2013.14

Рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению функциональной диспепсии / В.Т. Ивашкин, А.А. Шептулин, Т.Л. Лапина [и др.] // РЖГГК. — 2012. — Т. 22, № 3. — С. 80-92.

Aro Р. Functional dyspepsia impairs quality of life in the adult population / P. Aro, N.J. Talley // Alimentary Pharmacology & Therapeutics. — June 2011. — Vol. 33, Is. 11. — Р. 1215-1224. — Doi: 10.1111/j.1365-2036.2011.04640.x