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The article covers recent advances in the management of patients with liver disease of various origin. The use of direct-acting antiviral agents, as well as interferon-free regimens helps to achieve sustained viral response in most patients infected with hepatitis C virus. New data on about the use of statins, proton pump inhibitors, antibiotics in cirrhosis and portal hypertension are shown. A review of entirely new treatment of primary biliary cirrhosis, which is based on stimulation of farnesoid X receptors, was carried out. Clinical trials of alpha-pump, which improves the quality of life in patients with ascitis, as well as a fundamentally new device for extracorporeal detoxification, are presented.
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