Rotavirus-Induced Activation of the Defense Mechanisms of the Adaptive Immune System in Child’s Body

O.Ye. Abaturov, Yu.Yu. Stepanova

Abstract


The review describes the current understanding on the participation of the adaptive immune system in sanogenesis at rotavirus infection. It is shown that the leading component of the nonspecific defense mechanisms of the body that are involved in the development of rotavirus infection are such receptors as Toll-like receptors (TLR) and RIG-like receptors (RLR). Activation of TLR and RLR leads to the development of inflammation and induction of the synthesis of antimicrobial peptides.


Keywords


young children; rotavirus infection; adaptive immune system

References


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DOI: https://doi.org/10.22141/2308-2097.1.55.2015.80361

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