Features of the Diagnosis and Treatment of Acid-Related Disease in Patients with Diabetes Mellitus

S.M. Tkach

Abstract


The article considers the problem of the combined course of acid-related disorder of the gastrointestinal tract and diabetes mellitus (DM). The attention is paid to the fact that in most cases the treatment of gastroesophageal reflux disease and peptic ulcers in patients with diabetes mellitus should be carried out not as a proton pump inhibitor monotherapy, but as a comprehensive and differentiated treatment, taking into account etiological and pathogenetic features of the disease. When choosing the components of triple or quadruple therapy for the eradication of H.pylori in patients with DM among the group of proton pump inhibitors, it is desirable to give preference to pantoprazole (Zovanta). Pantoprazole does not interact with clarithromycin — basic antibiotic of H.pylori therapy. H.pylori therapy based on pantoprazole reduces the likelihood of side effects and increases the effectiveness of treatment.


Keywords


peptic ulcer disease; gastroesophageal reflux disease; eradication of H.pylori; diabetes mellitus; pantoprazole

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DOI: https://doi.org/10.22141/2308-2097.3.61.2016.79161

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