Portal Hypertensive Gastropathy (Literature Review)

Yu.M. Stepanov, O.V. Simonova, V.I. Didenko

Abstract


The article is dedicated to portal hypertensive gastropathy (PHG) — a secondary change of the mucousal and submucosal layer of the stomach on the background of liver cirrhosis (LC) of any origin etiology and concomitant portal hypertension. The review presents data concerning the history of the study of this pathology, epidemiology, pathogenesis, clinical manifestations, diagnostic techniques and treatment. It is shown that the disease is based on portal hypertension, which leads to disruption of the microcirculation of the gastric mucosa, and as a consequence — to congestion and venous stasis. The clinical course of PHG in most cases is asymptomatic. The main method of diagnosis is an endoscopy, which is based on certain macroscopic characteristics. The review considers basic endoscopic classification PHG. The main histological changes in PHG include dilation of the capillaries and venules in the mucosal and submucosal layer without significant inflammation. The course of PHG is dynamic. PHG complications include chronic ones and, rarely, acute bleedings. Treatment include medications, using non-selective beta-blockers


Keywords


liver cirrhosis; portal hypertensive gastropathy; endoscopic diagnosis.

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DOI: https://doi.org/10.22141/2308-2097.2.60.2016.74754

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