Features of Colon Microbiocenosis and Faecal Calprotectin Level in Patients with Chronic Inflammatory Bowel Diseases Depending on the Nutritional Status

N.V. Vinnyk, O.M. Tatarchuk, M.V. Stoikevych, V.Ye. Kudriavtseva, O.V. Sorochan


The article deals with an actual problem — the state of the microflora of the colon and faecal calprotectin level in patients with chronic inflammatory bowel diseases with different nutritional status. The study involved 76 patients with chronic inflammatory bowel diseases, including 28 patients with Crohn’s disease and 48 — with ulcerative colitis. We analyzed the findings depending on the nosology and nutritional status. It was found that among the patients of studied groups, patients with subcompensated form of dysbiosis dominated. Reducing the concentration of bifidobacteria in the colon content of patients from group III was detected more often — in 78.9 % of cases. Deficiency of lactobacilli was most often observed in patients of group II (92.3 %). The content of calprotectin was significantly increased in 84.2 % of patients, it positively correlated with the degree of severity of the disease and did not depend on their nutritional status.


chronic inflammatory bowel diseases; nutritional status; dysbiosis; microflora of the bowel; calprotectin.


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