Practical Approaches to the Management of Patients with Dyspepsia

S.M. Tkach


The article deals with the problem of the treatment of dyspepsia syndrome. Since recently the majority of patients with functional dyspepsia have a combination of symptoms of epigastric pain syndrome and postprandial distress syndrome, in practice combined therapy with proton pump inhibitors (PPIs) and prokinetics is used much more often as first-line empiric treatment. In this respect, administration of ready-to-use fixed combination, such as Omez D or Omez DCR containing IPPs and safe dose of domperidone, is very convenient.


dyspepsia; Maastricht consensus; proton pump inhibitors; prokinetics.


A randomized, double-blind, placebo- and positive-controlled, single- and multiple-dose, 4-way crossover study to evaluate the effects of domperidone on cardiac repolarization in healthy subjects. EudraCT number: 2012-001567-70, NCT No: NCT01643889 // Clin. Reg. No.: CR100893

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