DOI: https://doi.org/10.22141/2308-2097.53.4.2019.182407

Nutritional status of patients with chronic inflammatory bowel diseases and methods of its assessment

Yu.M. Stepanov, M.V. Titova, M.V. Stoikevich

Abstract


Chronic inflammatory bowel diseases, namely ulcerative colitis and Crohn’s disease, still remain one of the most complicated and pressing challenges of gastroenterology and coloproctology. As chronic inflammatory bowel disease are very common and number of patients with this disease increases, the scientists all over the world have to study the clinical features and pathogenesis of systemic lesions in ulcerative colitis and Crohn’s disease more intensively in order to develop some new methods for the diagnosis and treatment of such patients. The problem is that physicians do not focus enough attention on detection of the nutritional status disorders in this ca­tegory of patients. One of the causes for such situation is that there is no common standard for assessing nutritional status and risk of its disorders, which reduces possibility of analysis, generalization of research results and development of algorithms to correct these disorders. This paper reflects the principal methods to diagnose the nutritional status disorders. The possibilities of instrumental and laboratory research methods are shown. The attention was paid to gastrointestinal microbiota, as it is well known that small intestinal bacterial overgrowth and microflora disorders in large bowel play an important role and lead to the progression of malnutrition. The search was done using PubMed, Medline, Embase databases.

Keywords


review; chronic inflammatory bowel diseases; ulce­rative colitis; Crohn’s disease; nutritional status; anthropometry; questionnaire survey; laboratory methods

References


Sorochan OV, Stojkevych MV, Tatarchuk OM, Vinnyk NV. Treatment of patients with chronic inflammatory bowel disease with nutritional deficiency. Pivdennoukraïnsʹkij medičnij naukovij žurnal. 2017;16(16):86-89. (in Ukrainian).

Zakharash MP, Kucher ND, Zaharash YuM, et al., authors; Zakharash MP, editor. Khirurgiia: uchebnik [Surgery: a textbook]. Vinnitsya: Nova knyga; 2014. 360-365 pp. (in Russian).

Nagurnaya YaV. Comparative analysis of prevalence of inflammatory bowel diseases among the population of rural and industrial regions of Western Ukraine. Actual problems of modern medicine: Bulletin of Ukrainian Medical Stomatological Academy. 2015;(52):95-98. (in Ukrainian).

Stepanov YuM, Skyrda IYu, Petіshko OP. Chronic inflammatory bowel diseases: epidemiological features in Ukraine. Gastroenterologìa. 2017;51(2):97-105. doi: 10.22141/2308-2097.51.2.2017.101703. (in Ukrainian).

Nazarenko LI, Baranovsky AYu. Nutrition and inflammatory bowel diseases. Meditsinskiy Akademicheskiy Zhurnal. 2012;12(2):28-34. (in Russian).

Rudnev SG, Mozhokina GN, Bogorodskaya EM, Galygina NE, Nikolaev DV, Russkih OE. Investigation of nutritional status and body composition in patients with tuberculosis. Russian Pulmonology. 2013;(1):101-107. doi: 10.18093/0869-0189-2013-0-1-101-107. (in Russian).

Rocha R, Sousa UH, Reis TLM, Santana GO. Nutritional status as a predictor of hospitalization in inflammatory bowel disease: A review. World J Gastrointest Pharmacol Ther. 2019 Mar 7;10(2):50-56. doi: 10.4292/wjgpt.v10.i2.50.

Yadav DP, Kedia S, Madhusudhan KS, et al. Body Composition in Crohn's Disease and Ulcerative Colitis: Correlation with Disease Severity and Duration. Can J Gastroenterol Hepatol. 2017;2017:1215035. doi: 10.1155/2017/1215035.

Mijac DD, Janković GL, Jorga J, Krstić MN. Nutritional status in patients with active inflammatory bowel disease: prevalence of malnutrition and methods for routine nutritional assessment. Eur J Intern Med. 2010 Aug;21(4):315-9. doi: 10.1016/j.ejim.2010.04.012.

Stepanov YuM, Boiko TY, Sorochan OV, Stoikevych MV, Shkaredna AS. Bioimpedancemetry in evaluating nutritional status of patients with chronic inflammatory bowel diseases. Gastroenterologìa. 2015;(56):59-66. doi: 10.22141/2308-2097.2.56.2015.81498. (in Ukrainian).

Scaldaferri F, Pizzoferrato M, Lopetuso LR, et al. Nutrition and IBD: Malnutrition and/or Sarcopenia? A Practical Guide. Gastroenterol Res Pract. 2017;2017:8646495. doi: 10.1155/2017/8646495.

Sandhu A, Mosli M, Yan B, et al. Self-screening for malnutrition risk in outpatient inflammatory bowel disease patients using the Malnutrition Universal Screening Tool (MUST). JPEN J Parenter Enteral Nutr. 2016 May;40(4):507-10. doi: 10.1177/0148607114566656.

Kondrup J, Rasmussen HH, Hamberg O, Stanga Z; Ad Hoc ESPEN Working Group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003 Jun;22(3):321-36. doi: 10.1016/s0261-5614(02)00214-5.

Goost H, Vidakovic E, Deborre C, et al. Malnutrition in geriatric trauma patients: Screening methods in comparison. Technol Health Care. 2016;24(2):225-39. doi: 10.3233/THC1112.

Tran QC, Banks M, Hannan-Jones M, Do TND, Gallegos D. Validity of four nutritional screening tools against subjective global assessment for inpatient adults in a low-middle income country in Asia. Eur J Clin Nutr. 2018 Jul;72(7):979-985. doi: 10.1038/s41430-018-0217-8.

Donini LM, Poggiogalle E, Molfino A, et al. Mini-Nutritional Assessment, Malnutrition Universal Screening Tool, and Nutrition Risk Screening Tool for the Nutritional Evaluation of Older Nursing Home Residents. J Am Med Dir Assoc. 2016 Oct 1;17(10):959.e11-8. doi: 10.1016/j.jamda.2016.06.028.

Beck AM, Ovesen L, Osler M. The ‘Mini Nutritional Assessment’ (MNA) and the ‘Determine Your Nutritional Health’ Checklist (NSI Checklist) as predictors of morbidity and mortality in an elderly Danish population. Br J Nutr. 1999 Jan;81(1):31-6. doi: 10.1017/s0007114599000112.

Raguso CA, Maisonneuve N, Pichard C. Subjective Global Assessment (SGA): evaluation and followup of nutritional state. Rev Med Suisse Romande. 2004 Oct;124(10):607-10. (in French).

Spooren CEGM, Wintjens DSJ, de Jong MJ, et al. Risk of impaired nutritional status and flare occurrence in IBD outpatients. Dig Liver Dis. 2019 Sep;51(9):1265-1269. doi: 10.1016/j.dld.2019.05.024.

Adamenko EI, Silivonchik NN. Otsenka statusa pitaniia: uchebno-metodicheskoe posobie [Assessment of nutritional status: a training manual]. Minsk: BGMU; 2009. 7-11 pp. (in Russian).

Sergi G, De Rui M, Stubbs B, Veronese N, Manzato E. Measurement of lean body mass using bioelectrical impedance analysis: a consideration of the pros and cons. Aging Clin Exp Res. 2017 Aug;29(4):591-597. doi: 10.1007/s40520-016-0622-6.

Lemos T, Gallagher D. Current body composition measurement techniques. Curr Opin Endocrinol Diabetes Obes. 2017 Oct;24(5):310-314. doi: 10.1097/MED.0000000000000360.

Wagner DR. Ultrasound as a tool to assess body fat. J Obes. 2013;2013:280713. doi: 10.1155/2013/280713.

Bharadwaj S, Ginoya S, Tandon P, et al. Malnutrition: laboratory markers vs nutritional assessment. Gastroenterol Rep (Oxf). 2016 Nov;4(4):272-280. doi: 10.1093/gastro/gow013.

Keller U. Nutritional Laboratory Markers in Malnutrition. J Clin Med. 2019 May 31;8(6). pii: E775. doi: 10.3390/jcm8060775.

Lee JL, Oh ES, Lee RW, Finucane TE. Serum Albumin and Prealbumin in Calorically Restricted, Nondiseased Individuals: A Systematic Review. Am J Med. 2015 Sep;128(9):1023.e1-22. doi: 10.1016/j.amjmed.2015.03.032.

Gavrilina NS, Sedova GA, Kosyura SD. Malnutrition in patients with chronic pancreatitis. Likars’ka sprava. 2015;(1):122-127. (in Russian).

Abdullaev RIu, Komissarova OG. Tretyretin (prealbumin), its role in norm and pathology. Tuberkulez i bolezni legkikh. 2012;(2):3-7. (in Russian).

Dellière S, Cynober L. Is transthyretin a good marker of nutritional status? Clin Nutr. 2017 Apr;36(2):364-370. doi: 10.1016/j.clnu.2016.06.004.

Robinson MK, Trujillo EB, Mogensen KM, Rounds J, McManus K, Jacobs DO. Improving nutritional screening of hospitalized patients: the role of prealbumin. JPEN J Parenter Enteral Nutr. 2003 Nov-Dec;27(6):389-95; quiz 439. doi: 10.1177/0148607103027006389.

Maramygin DS, Sitnikov RV, Sumenkova DV. Adipokines in the pathogenesis of metabolic syndrome. Innovacionnaâ nauka. 2017;3(4):197-207. (in Russian).

Kaminskaia GO, Abdullaev RIu, Komissarova OG. Serum levels of transthyretin (prealbumin) in patients with pulmonary tuberculosis. Tuberkulez i bolezni legkikh. 2012;89(3):52-56. (in Russian).

Denisenko TL, Perfilova KM, Efimova EI, Bokarev AA. Bacteriological diagnostics of bacterial overgrowth syndrome in case of chronic pancreatitis. Medicinskij alʹmanah. 2010;(11):239-241. (in Russian).

Martynov VL, Khairdinov AKh, Kazarina NV. Insufficiency of Bauhin''s valve as the reason for small bowel bacterial overgrowth syndrome. Medicinskij alʹmanah. 2015;(36):46-50. (in Russian).

Ardatskaia MD. Intestine bacterial overgrowth syndrome and impaired absorption processes: pathogenetic nutritional therapy. Eksperimental'naia i klinicheskaia gastroenterologiia. 2009;(6):84-96. (in Russian).

Jandhyala SM, Talukdar R, Subramanyam C, Vuyyuru H, Sasikala M, Nageshwar Reddy D. Role of the normal gut microbiota. World J Gastroenterol. 2015 Aug 7;21(29):8787-803. doi: 10.3748/wjg.v21.i29.8787.

Sun M, Wu W, Liu Z, Cong Y. Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases. J Gastroenterol. 2017 Jan;52(1):1-8. doi: 10.1007/s00535-016-1242-9.

Bel'mer SV, Ardatskaia MD, Akopian AN. Korotkotsepochechnye zhirnye kisloty v lechenii funktsional'nykh zabolevanii kishechnika u detei: teoreticheskoe obosnovanie i prakticheskoe primenenie [Short-chain fatty acids in the treatment of functional intestinal diseases in children: theoretical basis and practical application]. Moscow: Prima Print; 2015. 48 p. (in Russian).

Morrison DJ, Preston T. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism. Gut Microbes. 2016 May 3;7(3):189-200. doi: 10.1080/19490976.2015.1134082.

Kumari R, Ahuja V, Paul J. Fluctuations in butyrate-producing bacteria in ulcerative colitis patients of North India. World J Gastroenterol. 2013 Jun 14;19(22):3404-14. doi: 10.3748/wjg.v19.i22.3404.

Wang W, Chen L, Zhou R, et al. Increased proportions of Bifi dobacterium and the Lactobacillus group and loss of butyrate-producing bacteria in infl ammatory bowel disease. J Clin Microbiol. 2014 Feb;52(2):398-406. doi: 10.1128/JCM.01500-13.

Primec M, Mičetić-Turk D, Langerholc T. Analysis of short-chain fatty acids in human feces: A scoping review. Anal Biochem. 2017 Jun 1;526:9-21. doi: 10.1016/j.ab.2017.03.007.

Lotti C, Rubert J, Fava F, Tuohy K, Mattivi F, Vrhovsek U. Development of a fast and cost-effective gas chromatography-mass spectrometry method for the quantification of short-chain and medium-chain fatty acids in human biofluids. Anal Bioanal Chem. 2017 Sep;409(23):5555-5567. doi: 10.1007/s00216-017-0493-5.




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