Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome

Yu.M. Stepanov, I.Ya. Budzak, I.A. Klenina


The article presents the issues related to gut microbiota and short-chain fatty acids in patients with irritable bowel syndrome. It was found that the faecal concentration of acetic, propionic, butyric acids is higher in patients with irritable bowel syndrome with diarrhea, compared with the patients without diarrhea syndrome. 83.3–88.9% of patients with various forms of irritable bowel syndrome presented with dysbiotic changes. The reduced concentration of Bifidobacterium species, mainly lactic acid bacteria, is more often registered in patients with diarrheal form. There is a certain correlation between the concentration of short-chain fatty acids and the content of Bifidobacterium, Lactobacillus, Candida and opportunistic bacteria.


irritable bowel syndrome; gut microbiota; dysbiosis; short-chain fatty acids

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Copyright (c) 2020 Yu.M. Stepanov, I.Ya. Budzak, I.A. Klenina

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